Solid Dosage Forms Services
When assessing a CDMO’s production capabilities, it’s important to pay close attention to the equipment it offers, but you should also take the team leading your project into account. From pre-formulation and clinical supply to commercial drug product manufacture and packaging, you can rely on United Science to deliver complex dosage forms with the ideal blend of technology, subject matter experience, and teamwork.
We can handle numerous dosage forms thanks to a wide range of manufacturing and packaging methods for pharmaceutical products. We are experts in packaging for completed goods as well as solid dosage forms, liquids, sterile and nonsterile gels, creams, and ointments. Your needs for clinical and commercialization support can be met by us.
Solid dosage forms from formulation to packaging
Solid dosage forms, such as tablets and capsules, remain the most common way to deliver both drugs and supplements. They are stable, easy to transport, and familiar to patients and consumers. They also have many variables to manage: particle size, blend uniformity, compression, coating, dissolution, and moisture sensitivity, among others. Our team supports solid dosage work from pre-formulation through clinical supply and commercial manufacture.
Formats we work with
- Tablets, including one-a-day tablets
- Effervescent formats
- Compressed formulations for pet products
- Pelletized formulations
- Hard capsules
- Bioavailable solid formats using our patent-pending bioavailable formulation method
Development steps
Pre-formulation. We study the active ingredient’s physical and chemical properties, including solubility, stability, and how it flows and compresses, to choose suitable excipients and processes.
Formulation. We develop prototypes and test them for content uniformity, hardness, disintegration, dissolution, and stability.
Process development. Our process development team defines the blending, granulation, compression, and coating parameters that control quality.
Clinical supply. We make clinical supplies of tablets and hard capsules in house at our FDA-registered Osceola facility.
Commercial manufacture and packaging. We support scale-up to commercial production and packaging of finished goods.
Analytical support. Our analytical development laboratory develops and validates the methods used to release and monitor the product.
Equipment and the team
Equipment matters when choosing a development partner, but so does the team running it. United Science combines formulation scientists, analytical chemists, and process engineers who also design and build process equipment. That mix helps when a solid dose process needs custom equipment or a change to existing equipment to work well at scale.
Solid dosage forms across industries
We develop solid dosage forms for pharmaceutical, OTC, and nutraceutical products. The level of control and documentation is matched to each product’s regulatory category.
Frequently asked questions
When is a solid dosage form the right choice?
When the ingredient is stable in solid form, the dose fits a reasonable tablet or capsule size, and the user is comfortable swallowing pills. If not, we may recommend softgels or a liquid dosage form.
Can you improve how a poorly soluble ingredient performs in a tablet?
Yes. Our bioavailable formulation method can be used in tablet formats for increased bioavailability.
Do you handle packaging?
Yes. We package finished goods in house in bottles, pouches, and jars.
Can you take over a product from another manufacturer?
Yes. We can review an existing formulation and process and support a transfer.